Oxandrolone is the trade name for an oral anabolic steroid with the chemical name Anavar. The appearance of the drug fell on the period of active research into anabolic steroids, which lasted from the 1950s to the 1980s. The aim of the research was to develop an anabolic compound that could be considered ideal. And the creators of Oxandrolone, perhaps, managed to get as close as possible to this goal. The drug has an excellent safety profile and the ratio of the risk of side effects to the expected benefit. This is one of the few steroids that can be prescribed for the treatment of children and women. In these two groups of patients, anabolic steroids are used extremely rarely due to the risk of adverse reactions.

For the first time, the drug Oxandrolone became known in 1962. A little later, it was introduced by Searle Laboratories (Pfizer Inc) under the brand name Anavar. Subsequently, various pharmaceutical companies have released Oxandrolone under other trade names. Among them: Protivar, Anatrophil, Antitriol, Lipidex and Lonavar. The drug has become one of the significant achievements of the pharmaceutical industry, which is confirmed by numerous data on the good tolerance of Oxandrolone by the majority of patients.


Anavar is a dihydrotestosterone derivative whose structure has been modified to give new properties to the compound. The first of the changes is C17-alpha alkylation, which makes it possible to take the drug orally. The second is the replacement of carbon in the 2nd position with oxygen, which enhanced the anabolic properties of the compound. The anabolic efficiency of Anavar is 3-6 times higher than that of Testosterone.

Any athlete strives to ensure that his muscle mass increases, the muscles themselves become more prominent and endurance indicators improve. For this purpose, many athletes take anabolic steroids. This is a very large group of drugs, which includes the highly effective Oxandrolone. It has a mild effect and has a lot of other names.

For those who are just starting out in athletic sports, it will serve as the best option. It can be safely attributed to safe steroids. When athletes apply drying, Oxandrolone should be used in combination with other drugs.

A two-month intake of the drug with a dosage of 30-60 mg will allow the body to provide sufficient rest from taking powerful drugs and everyday injections.

After application, the agent can be detected in the blood of athletes for 3-4 weeks. Therefore, it is advisable to give up the drug in advance before the competition. If you carry out a course reception, then it will be possible to observe how the hormonal background is leveled.

Chemical characteristics

Oxandrolone belongs to the Dihydrotestosterone (DHT) family of derivatives. In fact, it is Dihydrotestosterone with a methylation at position 17. This structural change allows the compound to cross the hepatic barrier when taken orally and makes it more resistant to hepatic metabolism.

Chemical characteristics

Another modification was made to the structure of the drug: in the first cycloalkane ring of the molecule, the second carbon atom was removed and replaced by oxygen. Thanks to this structural change, Oxandrolone occupies a special place among steroids, as it is the only compound in this group that has a direct modification in the ring structure: the carbon has been completely replaced by an atom of another element. Probably, this feature is the reason for the increase in the anabolic activity of the hormonal agent in comparison with the parent compound.

One of the mechanisms responsible for the high anabolic effectiveness of this modification of Oxandrolone (when compared with DHT) is believed to be an increase in resistance to the enzyme 3-hydroxysteroid dehydrogenase. This enzyme present in the muscles catalyzes the conversion of DHT to a non-anabolic metabolite. This explains the lack of anabolic effect of Dihydrotestosterone on muscle tissue. The compound is deactivated by 3-hydroxysteroid dehydrogenase before it acts on the androgen receptors in the muscles.

Effects of application

Taking Oxandrolone provides the following effects:

  • Hard dry muscles are perfectly built.
  • Significantly increased strength indicators.
  • Fat is burned effectively.
  • Somatotropin is intensively synthesized, which, as you know, is a growth hormone.

The positive thing that distinguishes this remedy from its other analogues is that the blood pressure when taken does not go beyond the norm. But this is not its only advantage. It also has other positive aspects:

Effects of application
  • It is not capable of causing any harm to the human body.
  • The action lasts up to 12 hours.
  • Reception does not affect the body’s synthesis of testosterone.
  • Beneficial effect on the nervous system.
  • Leads to increased strength.
  • Complete lack of fragrance.
  • Does not contribute to water retention in the body.
  • The muscles take on a more rigid character.

The tool has a weak androgenic activity. In terms of anabolic properties, it is 4 times ahead of testosterone. The ideal is to take the drug in the form of tablets. It has low toxicity to the liver. But, nevertheless, a parallel reception with hepatoprotectors is shown.

The drug does not aromatize at any dose. As already mentioned, a certain part of the testosterone in the blood is converted into estrogen. This aromatization process is expressed differently in different athletes, depending on the predisposition to it. With Oxandrolone, the muscles never acquire a watery appearance, which makes it possible to consider the drug a good tool in preparation for competitions. In this phase, first of all, it is important to keep the level of estrogen at a lower level, because. estrogens program the body, even with a low-calorie diet, to accumulate water.


Oxandrolone in reasonable doses does not give any side effects. This is understandable, because The drug was originally intended for women and children. This is one of the few steroids that does not cause premature growth retardation in children. it does not contribute to the closure of epophyseal connections, so the drug is used mainly in children to stimulate body growth and in women – with osteoporosis. The drug produces (if at all) very slight masculinization phenomena. This quality makes it a favorite remedy for athletes, because. at a dose of 10-15 mg per day, they rarely have outward manifestations of masculinity. Oxandrolone is very fond of bodybuilding and powerlifting athletes.

Side effects

If the daily dosage exceeds 80 mg, and the intake is carried out for more than 12 weeks, then the body’s production of testosterone may be suppressed. As a result, a decrease in libido can be observed.

Other undesirable manifestations are also possible. Basically, they are characterized by dyspeptic phenomena. A person may feel nauseous, his appetite decreases. Often there are pains in the form of gastric and intestinal colic. Headaches may join.

However, it should be said that such phenomena are extremely rare. This is due to the high safety of the drug.

Of course, the drug is quite effective, but not everyone can use it, since there are certain contraindications. These include the following states:

  • Cases of individual intolerance and hypersensitivity to the components of the composition.
  • Neoplasms of the prostate.
  • Atherosclerosis.
  • Renal and liver failure.
  • Any form of prostatitis.
  • The period of gestation.

In no case should you prescribe Oxandrolone yourself. This should only be done by a doctor. Of course, it is necessary to strictly observe everything that the doctor prescribes.